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27 Sep 2018 The quality of life of neuropathic pain patients is often aggravated by comorbidities such as sleep disorders, depression and anxiety compromise. (nano)-(micro)-emulsification, complexation (e.g., cyclodextrins), and encapsulation in lipid-based formulations (e.g., liposomes) It is administered at a dose that is equivalent to 2.7 mg THC and 2.5 mg CBD in each 100 μL ethanol spray.
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CBD has been reported to have several effects such as prolongation of sleep, anti-inflammation, anticonvulsant, anxiolytic, Self-micro- or self-nano-emulsifying drug delivery systems can produce nanoemulsion (NE) and improve the oral bioavailability of highly lipophilic compounds [18-20]. Ketoconazole, and Omeprazole on the pharmacokinetics of THC/CBD oromucosal spray in healthy volunteers.